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Very common Blood disease in Pakistan.

There are two Main Types:
– Beta – Thalassemia
– Alpha – Thalassemia’s
– Symptoms can include; Anemia…Low hemoglobin (low Hb)
– Bone deformities in the face
– Fatigue
– Growth failure
– Shortness of breath
– Spleenomegally


A physical exam may reveal a swollen (enlarged) spleen
Blood test:
1-Red blood cells will appear small and abnormally shaped when looked at under a microscope.
2-A complete blood count (CBC) reveals anemia.
3-A test called hemoglobin electrophoresis shows the presence of an abnormal form of hemoglobin


Treatment for thalassemia major often involves regular blood transfusions and folate supplements.

If you receive blood transfusions, you should not take iron supplements. Doing so can cause a high amount of iron to build up in the body, which can be harmful.
Persons who receive significant numbers of blood transfusions need a treatment called chelation therapy to remove excess iron from the body.
Bone marrow transplant may help treat the disease in some patients, especially children.


All young people should be tested before the marriage and counseled if they have thalassemia Risk to pass.